Sequence assignments in partially replicate design [Design Issues]

posted by Loky do – Egypt, 2020-07-19 01:33 (507 d 15:44 ago) – Posting: # 21746
Views: 1,562

Dears

In partially replicate 3-way design, FDA recommends using the following example for sequence assignments 1,2,3 --> (TRR, RTR, RRT), if we used different sequence assignments 1,2,3 --> (TRR, RRT, RTR), is this change significant? or is it ok as long as it's considered in statistical analysis?

Thanks in advance

Complete thread:

Activity
 Admin contact
21,788 posts in 4,557 threads, 1,548 registered users;
online 6 (0 registered, 6 guests [including 4 identified bots]).
Forum time: Wednesday 16:18 CET (Europe/Vienna)

There is no adequate defense, except stupidity,
against the impact of a new idea.    Percy Williams Bridgman

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5