Sequence assignments in partially replicate design [Design Issues]

posted by Loky do – Egypt, 2020-07-19 03:33 (1319 d 07:17 ago) – Posting: # 21746
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Dears

In partially replicate 3-way design, FDA recommends using the following example for sequence assignments 1,2,3 --> (TRR, RTR, RRT), if we used different sequence assignments 1,2,3 --> (TRR, RRT, RTR), is this change significant? or is it ok as long as it's considered in statistical analysis?

Thanks in advance

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