PK modeling in BE [NCA / SHAM]

posted by mittyri – Russia, 2020-07-19 02:24 (1369 d 20:04 ago) – Posting: # 21744
Views: 3,797

Hi Helmut,

❝ However, last year at the 10th American Conference on Pharmacometrics (20–23 October, Orlando) she gave a presentation “Evaluation of Model Based BioEquivalence (MBBE) statistical approaches for sparse designs PK studies” with a whoopy mean (!) Type I Error of 7.6%. :-(


Are you referring to this one?
Stan approach is a bit better, but still questionable

Kind regards,
Mittyri

Complete thread:

UA Flag
Activity
 Admin contact
22,986 posts in 4,823 threads, 1,668 registered users;
34 visitors (0 registered, 34 guests [including 5 identified bots]).
Forum time: 22:28 CEST (Europe/Vienna)

Art is “I”; science is “we”.    Claude Bernard

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5