PK modeling in BE [NCA / SHAM]

posted by mittyri – Russia, 2020-07-19 00:24 (378 d 21:26 ago) – Posting: # 21744
Views: 1,788

Hi Helmut,

» However, last year at the 10th American Conference on Pharmacometrics (20–23 October, Orlando) she gave a presentation “Evaluation of Model Based BioEquivalence (MBBE) statistical approaches for sparse designs PK studies” with a whoopy mean (!) Type I Error of 7.6%. :-(

Are you referring to this one?
Stan approach is a bit better, but still questionable

Kind regards,

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