Sometimes PK assessors ≈ scientists [Bioanalytics]

posted by Helmut Homepage – Vienna, Austria, 2020-07-17 16:11 (234 d 02:04 ago) – Posting: # 21734
Views: 2,628

Hi Ohlbe,

» There is indeed a high between-subject variability when it comes to PK assessors, sometimes even some within-subject variability, depending on their degrees of freedom :-D.
» In Europe: add the between-country variability.

Perfect description.
Last year I had a discussion with members of an European agency about irregular profiles and exclusion of data. They told me to regularly (‼) accept exclusion of “physiologically not plausible concentrations”. I was surprised and said that it is against the GL. Raised eyebrows…

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