how to use Loo Riegelman method and deconvolution [Dissolution / BCS / IVIVC]

posted by Gobardhan – India, 2020-07-16 15:31 (1351 d 22:24 ago) – Posting: # 21712
Views: 1,929

Dear vjkumar
Thank you for the reference and method explanation for deconvulation using loo riegelman method.
But I have stucked somewhere at the last time point as per the example given in the reference.
The %Absorbed value calculated by me is not matching with the value given and calculated in reference for last time point only.
So I think I am missing some parts like any assumption or hypothesis for consideration during the calculation for last time point.
Please help me to solve the calculation for last time point.

Thanks and Regards
Gobardhan

Complete thread:

UA Flag
Activity
 Admin contact
22,957 posts in 4,819 threads, 1,636 registered users;
104 visitors (0 registered, 104 guests [including 4 identified bots]).
Forum time: 12:56 CET (Europe/Vienna)

With four parameters I can fit an elephant,
and with five I can make him wiggle his trunk.    John von Neumann

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5