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posted by M.tareq  – 2020-07-16 01:36 (676 d 20:48 ago) – Posting: # 21706
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» In my protocols I state to use an estimated value anyway. This not only helps to correct for deviations from scheduled sampling times, but with ‘missings’ as well.

Is it possible to use a model-based approach to estimate the overall/typical value of Ke or CL and use that for prediction of such points ?

Or is it simpler to just perform a log-linear regression on averaged/all terminal points (3xTmax) and use that estimate to account for such deviations as defined in protocol.

Thanks

Mahmoud

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