Ratio calculation of fully replicate study [RSABE / ABEL]

posted by Mithu – India, 2020-07-09 12:46 (142 d 15:26 ago) – Posting: # 21663
Views: 1,546

Hello Sir,

» Then$$\overline{I_{11}}=0.5\times(7.578565+7.957261-7.734541-7.204848)=0.2982185$$and$$\overline{T_{11}/R_{11}}=\exp \overline{I_{11}}=\exp 0.2982185=1.347456$$

Thank you Sir, now i understand.

» Which leaves my second question open:
»
» » » Why on earth do you want to use Excel?

:-) Actually sir when we receive PK data from site (CRO), we check by using Excel. That's why i was using Excel for verification. Generally in average BE and partial replicate, we get it verified but for fully replicate study, i could not match the ratio.

This is the story.

thank you for your kind guidance and help.

regards,

Mithu


Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5[Helmut]

Complete thread:

Activity
 Admin contact
21,216 posts in 4,427 threads, 1,481 registered users;
online 7 (0 registered, 7 guests [including 4 identified bots]).
Forum time: Sunday 03:13 CET (Europe/Vienna)

Half the harm that is done in this world
Is due to people who want to feel important.    T. S. Eliot

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5