Bioequivalence and Bioavailability Forum

Concentration Statistics - BQL substitution [General Statistics]

posted by SaraCHenriques – Portugal, 2020-07-01 14:37 (482 d 18:25 ago) – Posting: # 21631
Views: 3,683

Hi everyone,

What is your opinion on below quantification limit (BQL) substitution for concentration data summary statistics, by timepoint?

Zero substitution is the one I have seen the most, however, I don't think it is suitable for the calculation of geometric means.

Could you give me your opinion on this matter?

Many thanks!

—
Sara

Complete thread:

Concentration Statistics - BQL substitutionSaraCHenriques 2020-07-01 14:37 [General Statistics]
- Concentration Statistics - BQL substitution Helmut 2020-07-01 15:27
  - Concentration Statistics - BQL substitution martin 2020-07-02 09:37
    - Data imputation Helmut 2020-07-02 11:15
    - Concentration Statistics - BQL substitution ElMaestro 2020-07-02 13:48
      - Concentration Statistics - BQL substitution martin 2020-07-02 14:52
    - Concentration Statistics - BQL substitution Ben 2020-07-07 16:37
      - BQL in BE and PK modeling Helmut 2020-07-08 10:23
      - Concentration Statistics - BQL substitution ElMaestro 2020-07-08 11:35
      - Roger again mittyri 2020-07-08 12:03

Concentration Statistics - BQL substitution [General Sta­tis­tics]

Complete thread:

Concentration Statistics - BQL substitution [General Statistics]