random effects in BEAR (lme_lm.mod.r) [R for BE/BA]

posted by jabriges – US, 2020-06-24 19:46 (394 d 20:55 ago) – Posting: # 21577
Views: 1,763

I have a question about getting subject level random effect. The call of lme() in lme_lm.mod.r uses

random=~drug - 1|subj

I'm not seeing how this gives you a random effect for each subject. I understand the -1 removes the intercept, but doesn't the inclusion of drug there make the random effect differ by formulation, and hence period (for the same subject)?
Any insight appreciated.

-Jay

Complete thread:

Activity
 Admin contact
21,589 posts in 4,512 threads, 1,530 registered users;
online 6 (0 registered, 6 guests [including 3 identified bots]).
Forum time: Saturday 16:41 CEST (Europe/Vienna)

There are no dangerous thoughts;
thinking itself is dangerous.    Hannah Arendt

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5