Bioequivalence and Bioavailability Forum • steady state for modified release

steady state for modified release [Regulatives / Guidelines]

posted by apapanas – Greece, 2020-06-24 16:25 (1395 d 15:25 ago) – Posting: # 21574
Views: 3,025

Dear Helmut,

Is there a threshold value for linearity indexes (AUC0-tau,ss / AUC0-inf, SD) over which the superposition principle is no longer applicable?

Thank you in advance.

Kindest regards,
Antigoni

Complete thread:

steady state for modified release Kelen 2019-09-20 20:04 [Regulatives / Guidelines]
- steady state for modified release Helmut 2019-09-23 10:04
  - steady state for modified releaseapapanas 2020-06-24 14:25
    - Superposition principle Helmut 2020-06-24 14:38
      - Superposition principle apapanas 2020-06-24 15:32