MRT and Gravity duration [NCA / SHAM]

posted by mittyri – Russia, 2020-06-14 20:24 (336 d 01:55 ago) – Posting: # 21539
Views: 3,298

Dear Astea,

» MRT is a most common PK parameters that compels to look at the AUMC. There existed approaches4 to use MRT instead of T1/2 in order to choose the appropriate washout period.

Just my 2 cents regarding MRT. You cannot estimate it for non-IV ways of administration. For non-IV that parameter is called 'gravity duration', since includes both MIT and MRT. See here for discussion.

Kind regards,
Mittyri

Complete thread:

Activity
 Admin contact
21,462 posts in 4,487 threads, 1,514 registered users;
online 12 (0 registered, 12 guests [including 8 identified bots]).
Forum time: Sunday 22:20 UTC (Europe/Vienna)

Garbage in, garbage out.
It’s very very simple.    Anders Fuglsang

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5