Phoenix: One-sided tests [Software]

posted by Helmut Homepage – Vienna, Austria, 2020-06-14 12:05 (336 d 10:45 ago) – Posting: # 21538
Views: 1,823

Hi Sara,

sorry for not replying earlier.

» […] how to perform a non-inferiority analysis for this data, on Phoenix WinNonlin.

Not directly supported in Phoenix. However, there is a simple workaround. Non-inferiority tests (and non-superiority as well) are one-sided. Perform the BE-analysis as usual in Phoenix (i.e., two-sided for equivalence at α 0.05) and assess whether the lower confidence limit is ≥80.00% of the reference. Ignore the upper limit.

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