OT: Bias of AUCt, AUCall, pAUC [Regulatives / Guidelines]
Hi again Helmut,
there is no doubt that AUC calculation can be biased. Whether the ln difference or ratio is biased, generally, is another matter and this is where I meant to draw the attention - this is the BE outcome. If one could make a case for saying that this bias affects T more often or to a larger extent than it affects R, generally, then that is where the use of this approach would be not just ugly but even worse also clearly biased.
I am not aware this would or should be the case.
there is no doubt that AUC calculation can be biased. Whether the ln difference or ratio is biased, generally, is another matter and this is where I meant to draw the attention - this is the BE outcome. If one could make a case for saying that this bias affects T more often or to a larger extent than it affects R, generally, then that is where the use of this approach would be not just ugly but even worse also clearly biased.
I am not aware this would or should be the case.
—
Pass or fail!
ElMaestro
Pass or fail!
ElMaestro
Complete thread:
- AUCt not covering at least 80% of AUCinf ratnakar1811 2013-03-05 08:30 [Regulatives / Guidelines]
- AUCt not covering at least 80% of AUCinf d_labes 2013-03-05 11:12
- AUCt not covering at least 80% of AUCinf ratnakar1811 2013-03-06 08:50
- AUCt not covering at least 80% of AUCinf ElMaestro 2013-03-06 11:10
- Science vs. regulations Helmut 2013-03-06 14:30
- Science vs. regulations cakhatri 2013-03-10 08:59
- ratio = difference of logs! Helmut 2013-03-11 01:17
- Science vs. (EMA) GL aka PK primer Helmut 2013-03-11 03:17
- Science vs. regulations qualityassurance 2020-04-23 14:11
- Science vs. regulations Helmut 2020-04-23 17:32
- Science vs. regulations Achievwin 2020-05-07 22:59
- Science vs. regulations Helmut 2020-05-07 23:54
- Science vs. regulations Achievwin 2020-05-07 22:59
- Science vs. regulations Helmut 2020-04-23 17:32
- Science vs. regulations cakhatri 2013-03-10 08:59
- AUCt not covering at least 80% of AUCinf Brus 2018-11-20 13:01
- AUCt not covering at least 80% of AUCinf Astea 2020-06-05 19:05
- So what? Helmut 2020-06-06 12:02
- Carrot and whip Astea 2020-06-06 21:11
- Gedankenexperiment Helmut 2020-06-07 12:41
- Dead dogs mittyri 2020-06-07 20:32
- Aber meine Herren das ist keine physik Astea 2020-06-08 00:08
- Aber meine Dame, das ist alles Unsinn! Helmut 2020-06-08 01:04
- Bizarre paper Helmut 2020-06-08 12:43
- Bizarre paper ElMaestro 2020-06-08 15:33
- OT: Bias of AUCt, AUCall, pAUC Helmut 2020-06-08 15:53
- OT: Bias of AUCt, AUCall, pAUCElMaestro 2020-06-09 08:45
- OT: Bias of AUCs; example Helmut 2020-06-09 14:07
- OT: Bias of AUCt, AUCall, pAUCElMaestro 2020-06-09 08:45
- OT: Bias of AUCt, AUCall, pAUC Helmut 2020-06-08 15:53
- Maxwell's demon Astea 2020-06-12 14:15
- Bizarre paper ElMaestro 2020-06-08 15:33
- Dead dogs Helmut 2020-06-08 10:40
- Aber meine Herren das ist keine physik Astea 2020-06-08 00:08
- Dead dogs mittyri 2020-06-07 20:32
- Gedankenexperiment Helmut 2020-06-07 12:41
- Carrot and whip Astea 2020-06-06 21:11
- So what? Helmut 2020-06-06 12:02
- AUCt not covering at least 80% of AUCinf Astea 2020-06-05 19:05
- AUCt not covering at least 80% of AUCinf ratnakar1811 2013-03-06 08:50
- AUCt not covering at least 80% of AUCinf d_labes 2013-03-05 11:12