Problems with PASS [Software]

posted by ElMaestro  – Belgium?, 2020-05-15 13:01 (197 d 05:23 ago) – Posting: # 21441
Views: 2,168

Hi Hötzi,

I could be wrong but...

PASS may be assuming this is a case of two sample t-test-like-scenario, where it does not take into consideration that the actual model causes additional reduction of df's.

You may be able to approximately reproduce PASS' result if you can override the df's in PowerTOST. I would still anyday say PowerTOST is more right than PASS, of course.

I could be wrong, but...

Best regards,
ElMaestro

No, of course you do not need to audit your CRO if it was inspected in 1968 by the agency of Crabongostan.

Complete thread:

Activity
 Admin contact
21,216 posts in 4,427 threads, 1,482 registered users;
online 15 (1 registered, 14 guests [including 11 identified bots]).
Forum time: Saturday 17:25 CET (Europe/Vienna)

Science may be described as the art of systematic over-simplification –
the art of discerning what we may with advantage omit.    Karl R. Popper

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5