Missing samples [Study Assessment]
thanks for your reply
❝ This guy is clearly not participating PP, his AUC is not outright a meaningful indicator of product performance, so out he goes, I think.
Yes, he actually missed the terminal phase, his AUC0-t is about 17% of his AUC0-inf, also check his figure
What we could do?
1- Extrapolate to 72 h
2- Use AUC common (0-12)
3- or based on the results of the current study could we make another stage on 12 subjects (knowing that the first one was performed on 24)?
4- Exclude the subject from stat evaluation of AUC(0-t) and include in all other parameters (as long as it does not jeopardize the acceptance of the study)
looking forward to your opinion
- Outlier in BE study Amira Gouda 2020-04-28 15:36 [Study Assessment]
- Outlier in BE study mittyri 2020-04-29 11:50
- Outlier in BE study Ohlbe 2020-04-29 15:19