Common sense instead of statistics [Software]

posted by Helmut Homepage – Vienna, Austria, 2020-04-27 13:45 (946 d 18:49 ago) – Posting: # 21351
Views: 5,843

Hi vixen,

❝ I like Helmut's suggestion to assess achievement of SS for individual subjects.

My suggestion dates back to 2007. A while ago…
I don’t use it since 2010 and don’t recommend it any more (see this presentation, slide 14). Furthermore, the EMA stated:*

A specific statistical method to assure that steady state has been reached is not considered necessary in bioequivalence studies. Descriptive data is sufficient.

❝ I wonder though whether I should evaluate the Cpds on a normal or logarithmic scale.

Normal – otherwise you cannot deal with BQLs and missings.

❝ What is your approach?

See the presentation.

Dif-tor heh smusma 🖖🏼 Довге життя Україна! [image]
Helmut Schütz

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

UA Flag
 Admin contact
22,418 posts in 4,693 threads, 1,598 registered users;
11 visitors (0 registered, 11 guests [including 6 identified bots]).
Forum time: 07:34 CET (Europe/Vienna)

Intellect distinguishes between the possible and the impossible;
reason distinguishes between the sensible and the senseless.
Even the possible can be senseless.    Max Born

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz