long acting Injection [Design Issues]

posted by jag009  – NJ, 2020-04-21 23:06 (1462 d 21:49 ago) – Posting: # 21342
Views: 1,626

Hi,

❝ But if it is mentioned in monograph that half-life is 17 days following single dose and 46 days after multiple dose, then which half-life we should consider while designing multiple dose study? In the same monograph, it is also stated that steady state is achieved after 4th dose on injection.


Have you found out why the increase in half-life?

J

Complete thread:

UA Flag
Activity
 Admin contact
22,993 posts in 4,828 threads, 1,652 registered users;
64 visitors (1 registered, 63 guests [including 5 identified bots]).
Forum time: 20:56 CEST (Europe/Vienna)

If you don’t like something change it;
if you can’t change it, change the way you think about it.    Mary Engelbreit

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5