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Hi,
» But if it is mentioned in monograph that half-life is 17 days following single dose and 46 days after multiple dose, then which half-life we should consider while designing multiple dose study? In the same monograph, it is also stated that steady state is achieved after 4th dose on injection.
Have you found out why the increase in half-life?
J
» But if it is mentioned in monograph that half-life is 17 days following single dose and 46 days after multiple dose, then which half-life we should consider while designing multiple dose study? In the same monograph, it is also stated that steady state is achieved after 4th dose on injection.
Have you found out why the increase in half-life?
J
Complete thread:
- long acting Injection pankajsojitra 2020-04-19 11:15 [Design Issues]
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- long acting Injectionjag009 2020-04-21 21:06
- long acting Injection pankajsojitra 2020-04-23 14:40
- long acting Injectionjag009 2020-04-21 21:06
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