A vs B [Design Issues]

posted by mittyri – Russia, 2020-02-03 22:05 (1030 d 11:08 ago) – Posting: # 21136
Views: 2,632

Hi John,

citing our Hero:

If one is really interested in λz and has no SD-phase in the study, sampling should continue until concentrations from previous doses are washed out – I would expect any estimate within the MD-profile to be biased towards faster elimination.

❝ I have seen both designs but I (and my former bosses) prefer method A. The only drawback I see from A is it takes longer time.


why does A take longer time?


Edit: Changed to internal link; see also this post #7[Helmut]

Kind regards,
Mittyri

Complete thread:

UA Flag
Activity
 Admin contact
22,418 posts in 4,693 threads, 1,598 registered users;
17 visitors (0 registered, 17 guests [including 4 identified bots]).
Forum time: 09:14 CET (Europe/Vienna)

Intellect distinguishes between the possible and the impossible;
reason distinguishes between the sensible and the senseless.
Even the possible can be senseless.    Max Born

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5