Bioequivalence and Bioavailability Forum • Great discussion

Great discussion [Design Issues]

posted by Helmut – Vienna, Austria, 2020-01-02 17:14 2a02:8388:6bc2:ce80:ecf1:7da1:2052:4299 – Posting: # 21054
Views: 1,453

Hi ElMaestro,

» Is a crossparticipation effort truly necessary across EU?

Yes. In my CRO we had occasionally volunteers from Budapest (2:40 by train), Brno (2:10), and Bratislava (1:10).

» Of course DNA traces present in plasma are direct markers of subject identity posing huge technical …

No cellular compounds in plasma → bad luck. DNA identification was our first idea when we suspected a case of sample mix-up. Well, …

» … and practical difficulties …

Not to forget legal issues. Even if you manage to get a blood sample, in Germany & Austria you can’t simply start sequencing. Needs another ICF.

» … and that in itself is a discussion for another thread.

Yep.

» Can you guys think of any other biomarker/indicator unrelated to blood loss or the regenerative process?

No, sorry.

—
Cheers,
Helmut Schütz

The quality of responses received is directly proportional to the quality of the question asked. 🚮
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Complete thread:

Normal Reference Range Vs Pre-defined site normal values cakhatri 2019-12-17 11:35 [Design Issues]
- Normal Reference Range Vs Pre-defined site normal values ElMaestro 2019-12-17 23:21
- Hb level Ohlbe 2019-12-29 17:04
  - OT Helmut 2019-12-29 18:49
  - Hb level nobody 2019-12-31 10:47
  - Hb level ElMaestro 2019-12-31 15:19
    - Hb level nobody 2019-12-31 15:46
      - Hb level ElMaestro 2019-12-31 17:21
        
        Hb level nobody 2019-12-31 17:26
        Participation databases Helmut 2019-12-31 18:01
        
        Participation databases ElMaestro 2019-12-31 20:21
        
        Participation databases Helmut 2020-01-01 10:23
        
        Participation databases ElMaestro 2020-01-01 12:23
        
        Participation databases nobody 2020-01-02 10:35
        Participation databases Ohlbe 2020-01-02 12:18
        
        National databases‽ Helmut 2020-01-02 13:06
        
        Great discussion ElMaestro 2020-01-02 16:31
        
        Great discussion Ohlbe 2020-01-02 16:57
        
        Great discussion ElMaestro 2020-01-02 18:19
        
        WTF 😡 Helmut 2020-01-02 18:42
        
        Great discussionHelmut 2020-01-02 17:14
        
        National databases‽ Ohlbe 2020-01-02 16:36