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RegisterSum of residuals ~ ε [Design Issues]
Hi both,
» I disagree. In the model ε = 0. However in the fit, the sum of residuals is only asymptotically 0. We shouldn’t speak of bias when we obtain something sufficiently close to the numeric resolution of the machine.
Perhaps I am getting it wrong; the sentence above sounds a little off and I have a feeling you may not be discussing the same thing?
The sum of residuals for a fitted normal linear model will be zero. Not asymptotically. If you sum them in R or any other software you will get zero, be it either like zero-zero or effectively zero, depending on the implementation.
This is because the underlying assumption is that epsilon be distributed with mean zero. If we end up with a non-zero sum, I'd say we have screwed up somewhere.
Try
» I disagree. In the model ε = 0. However in the fit, the sum of residuals is only asymptotically 0. We shouldn’t speak of bias when we obtain something sufficiently close to the numeric resolution of the machine.
Perhaps I am getting it wrong; the sentence above sounds a little off and I have a feeling you may not be discussing the same thing?
The sum of residuals for a fitted normal linear model will be zero. Not asymptotically. If you sum them in R or any other software you will get zero, be it either like zero-zero or effectively zero, depending on the implementation.
This is because the underlying assumption is that epsilon be distributed with mean zero. If we end up with a non-zero sum, I'd say we have screwed up somewhere.
Try
sum(resid(M))—
I could be wrong, but...
Best regards,
ElMaestro
No, of course you do not need to audit your CRO if it was inspected in 1968 by the agency of Crabongostan.
I could be wrong, but...
Best regards,
ElMaestro
No, of course you do not need to audit your CRO if it was inspected in 1968 by the agency of Crabongostan.
Complete thread:
- Should those subjects have only one period data be included in BE analysis? ssussu 2019-12-06 10:58 [Design Issues]
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- No way! But... Beholder 2019-12-06 12:36
- No way! But... ElMaestro 2019-12-06 13:14
- No way! But... Helmut 2019-12-06 14:47
- No way! But... PharmCat 2019-12-06 23:46
- No way! But... wienui 2019-12-07 04:01
- EMA guideline: no way...: mittyri 2019-12-07 20:58
- EMA guideline: no way...: wienui 2019-12-09 05:25
- EMA guideline: no way...: mittyri 2019-12-07 20:58
- Slightly off topic, but related :-) ElMaestro 2019-12-08 01:31
- Slightly off topic, but related :-) Shuanghe 2019-12-09 12:00
- Slightly off topic, but related :-) PharmCat 2019-12-09 15:13
- Slightly off topic, but related :-) ElMaestro 2019-12-21 15:02
- Slightly off topic, but related :-) PharmCat 2019-12-22 01:12
- 2.220446e-16 ≈ 0 Helmut 2019-12-22 10:37
- The optional tolerance argument ElMaestro 2019-12-23 14:37
- 2.220446e-16 ≈ 0 PharmCat 2019-12-24 14:18
- Sum of residuals ~ ε Helmut 2019-12-24 14:54
- Sum of residuals ~ εElMaestro 2019-12-24 15:10
- Wrong terminology Helmut 2019-12-28 13:55
- Sum of residuals ~ ε PharmCat 2019-12-24 18:40
- Sum of residuals ~ εElMaestro 2019-12-24 15:10
- Sum of residuals ~ ε Helmut 2019-12-24 14:54
- Slightly off topic, but related :-) ElMaestro 2019-12-21 15:02
- No way! But... wienui 2019-12-07 04:01
- No way! But... PharmCat 2019-12-06 23:46
- No way! But... Helmut 2019-12-06 14:47
- No way! But... ElMaestro 2019-12-06 13:14
- No way! But... Beholder 2019-12-06 12:36
Ing. Helmut Schütz