Cmax ER = Cmax IR ? [Regulatives / Guidelines]

posted by jag009  – NJ, 2019-12-09 18:15 (780 d 19:10 ago) – Posting: # 20967
Views: 2,105

Hi,

» We have: four maximums and four minimums for IR and one maximum and one minimum for ER

If I understand your question correctly... In general, your trough (Cmin) for ER should be similar (or above) your Cmin of the IR in terms of level (is your a 24hr once daily? If so, then the Cmin of ER at 24 should be similar to Cmin of IR at 24). Your ER should also show less fluctuation than IR (you should).

J

Complete thread:

Activity
 Admin contact
21,854 posts in 4,573 threads, 1,555 registered users;
online 13 (0 registered, 13 guests [including 11 identified bots]).
Forum time: Friday 13:25 CET (Europe/Vienna)

No fret, no strain, no pain.
If you want my interest, interest me.
If you just want my presence, pay me.    Robert Mitchum

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5