No way! But... [Design Issues]

posted by Helmut Homepage – Vienna, Austria, 2019-12-06 15:47 (1207 d 23:24 ago) – Posting: # 20942
Views: 5,529

Ahoy my capt’n and welcome back to this side of the pond!

❝ I do not know why there is a regulatory tradition for only using completers …


Those days when studies were evaluated by a paired t-test with a pocket calculator?

❝ – I would say there is even a potential scientific and ethical advantage of using all period data.


Correct. If we would be allowed (pun!) to use a mixed-effects model. Patterson and Jones argued against this doubtful practice and the ethical implications of discarding data.*



Dif-tor heh smusma 🖖🏼 Довге життя Україна! [image]
Helmut Schütz
[image]

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

UA Flag
Activity
 Admin contact
22,557 posts in 4,724 threads, 1,607 registered users;
19 visitors (0 registered, 19 guests [including 11 identified bots]).
Forum time: 16:11 CEST (Europe/Vienna)

Science is wonderfully equipped to answer the question “How?”
but it gets terribly confused when you ask the question “Why?”    Erwin Chargaff

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5