No way! But... [Design Issues]

posted by Helmut Homepage – Vienna, Austria, 2019-12-06 15:47 (1465 d 16:06 ago) – Posting: # 20942
Views: 5,781

Ahoy my capt’n and welcome back to this side of the pond!

❝ I do not know why there is a regulatory tradition for only using completers …


Those days when studies were evaluated by a paired t-test with a pocket calculator?

❝ – I would say there is even a potential scientific and ethical advantage of using all period data.


Correct. If we would be allowed (pun!) to use a mixed-effects model. Patterson and Jones argued against this doubtful practice and the ethical implications of discarding data.*



Dif-tor heh smusma 🖖🏼 Довге життя Україна! [image]
Helmut Schütz
[image]

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

UA Flag
Activity
 Admin contact
22,823 posts in 4,786 threads, 1,632 registered users;
38 visitors (0 registered, 38 guests [including 6 identified bots]).
Forum time: 07:53 CET (Europe/Vienna)

In these matters the only certainty is
that nothing is certain.    Pliny the Elder

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5