No way! But... [Design Issues]

posted by ElMaestro  – Belgium?, 2019-12-06 12:14 (327 d 08:04 ago) – Posting: # 20941
Views: 3,507

Hello, both,

» » At this situation, should this subject's data with one period be included in the BE assessment?
»
» No, you could not.

We do not need a T-R comparison in each subject to do an analysis. We are just stuck in that paradigm. We could in principle fit a model with missing period data. And all data could be used for the calculation of the CI.
I do not know why there is a regulatory tradition for only using completers - I would say there is even a potential scientific and ethical advantage of using all period data.

I could be wrong, but...

Best regards,
ElMaestro

No, of course you do not need to audit your CRO if it was inspected in 1968 by the agency of Crabongostan.

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