Automatic → visual inspection/adjustment [🇷 for BE/BA]

posted by yjlee168 Homepage – Kaohsiung, Taiwan, 2019-11-20 19:48 (1110 d 20:09 ago) – Posting: # 20845
Views: 5,094

Dear Helmut,

❝ Why not? I do that for decades and never got a question from any agency.

I see. for decades? :-D

❝ — Any [sic] automatic algo performs badly for “flat” profiles (e.g., modified release) and terrible for multiphasic products.

Right. It is indeed quite possible for some modified releases. It makes sense.

❝ — Visual inspection / adjustment recommended in the literature.

❝ — Stated not only my SOP but also in the protocol: Automatic method first (I’m lazy and in most cases it works), adjustment second.

Smart strategy. :ok: Thanks for your messages. I learned.

All the best,
-- Yung-jin Lee
bear v2.9.1:- created by Hsin-ya Lee & Yung-jin Lee
Kaohsiung, Taiwan
Download link (updated) -> here

Complete thread:

UA Flag
 Admin contact
22,428 posts in 4,694 threads, 1,598 registered users;
18 visitors (0 registered, 18 guests [including 9 identified bots]).
Forum time: 15:57 CET (Europe/Vienna)

Statistics is the art of never having to say you’re wrong.
Variance is what any two statisticians are at.    C.J. Bradfield

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz