PKNCA Package usage [🇷 for BE/BA]

posted by yjlee168 Homepage – Kaohsiung, Taiwan, 2019-11-20 15:35 (1565 d 10:41 ago) – Posting: # 20840
Views: 5,019

Hi sury

❝ ...

❝ And i have tried to estimate the PK parameters using BEAR package. but it is not getting the same results as that of the WinNonlin


Which method did you use for AUC calculation with bear? 'linear-up/log-down' or 'all linear' trapezoidal method? The default method in bear is 'linear-up/log-down'. The other issue to cause the difference is the method used to estimate lambda z.

All the best,
-- Yung-jin Lee
bear v2.9.1:- created by Hsin-ya Lee & Yung-jin Lee
Kaohsiung, Taiwan https://www.pkpd168.com/bear
Download link (updated) -> here

Complete thread:

UA Flag
Activity
 Admin contact
22,919 posts in 4,807 threads, 1,641 registered users;
21 visitors (0 registered, 21 guests [including 5 identified bots]).
Forum time: 02:17 CET (Europe/Vienna)

The analysis of variance is not a mathematical theorem,
but rather a convenient method of arranging the arithmetic.    R.A. Fisher

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5