More on IS response variations [Regulatives / Guidelines]

posted by Helmut Homepage – Vienna, Austria, 2019-11-12 13:41 (804 d 23:04 ago) – Posting: # 20791
Views: 3,456

Hi ElMaestro,

» As a general rule the S:N become more unfavourable as the column ages and peak separation suffers. This affects the identifcation of peaks and their integration. It will be more pronounced for the analyte near the LLOQ than for the IS.

I stand corrected. :-D

Dif-tor heh smusma 🖖
Helmut Schütz
[image]

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

Activity
 Admin contact
21,854 posts in 4,573 threads, 1,554 registered users;
online 15 (1 registered, 14 guests [including 15 identified bots]).
Forum time: Tuesday 12:46 CET (Europe/Vienna)

I love deadlines.
I love the whooshing sound they make
as they go by.    Douglas Adams

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5