G matrix [General Sta­tis­tics]

posted by mittyri  – Russia, 2019-11-03 02:38 (2022 d 22:59 ago) – Posting: # 20748
Views: 6,167

Dear Patel,

❝ Is there any role of G-matrix in the calculation of LSM?


Even with one sample modified the model coefficients are changed. G matrix specifies variance-covariance matrix G and it is used to specify subject-specific effects.
With model changed covariance matrix is also changed, thus, you see the difference. Since MIXED statement uses some algos to achieve convergence, some changes in points could be crucial even if they are insignificant for reviewer.

Kind regards,
Mittyri

Complete thread:

UA Flag
Activity
 Admin contact
23,424 posts in 4,927 threads, 1,673 registered users;
210 visitors (0 registered, 210 guests [including 12 identified bots]).
Forum time: 02:38 CEST (Europe/Vienna)

Nothing shocks me. I’m a scientist.    Harrison Ford (as Indiana Jones)

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5