G matrix [General Sta­tis­tics]

posted by mittyri – Russia, 2019-11-03 01:38 (284 d 23:51 ago) – Posting: # 20748
Views: 2,097

Dear Patel,

» Is there any role of G-matrix in the calculation of LSM?

Even with one sample modified the model coefficients are changed. G matrix specifies variance-covariance matrix G and it is used to specify subject-specific effects.
With model changed covariance matrix is also changed, thus, you see the difference. Since MIXED statement uses some algos to achieve convergence, some changes in points could be crucial even if they are insignificant for reviewer.

Kind regards,
Mittyri

Complete thread:

Activity
 Admin contact
21,016 posts in 4,380 threads, 1,460 registered users;
online 17 (0 registered, 17 guests [including 7 identified bots]).
Forum time: Friday 02:30 CEST (Europe/Vienna)

He who fails to plan
is planning to fail.    Winston Churchill

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5