median Tmax [Study Per­for­mance]

posted by mittyri – Russia, 2019-10-17 00:01 (774 d 22:53 ago) – Posting: # 20698
Views: 2,975

Hi Helmut,

» For the IR formulation most people opt at two times the median tmax.

that's right, but in such case the PK scientist should know the median before the analysis starts, should he? Or to exclude the subject after PK analysis, when the median is calculated? Or should he use the published median Tmax?

Kind regards,
Mittyri

Complete thread:

Activity
 Admin contact
21,778 posts in 4,555 threads, 1,547 registered users;
online 10 (0 registered, 10 guests [including 8 identified bots]).
Forum time: Monday 21:55 CET (Europe/Vienna)

Mediocrity knows nothing higher than itself,
but talent instantly recognizes genius.    Arthur Conan Doyle

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5