AUC-apical? [Software]

posted by Aisha.ma – United Arab Emirates, 2019-10-07 18:43 (744 d 03:37 ago) – Posting: # 20677
Views: 2,667

Hi Helmut,

» BTW, are you referring to this guideline?

Maybe the sponsor had consult this guideline before designing the study . Gir is the glucose-infusion rate.

» Just to clarify: Are you interested in the yellow area?
»

[image]


» Doesn’t look like your GIR cause that’s a PK profile but you get the idea. IIRC, this was called AUCapical by the “Two Lászlós” (Endrényi and Tóthfalusi). Have to dig it out.

I need to know time to 50% of GIR-AUC0-8. At the begining, I think that I can use summary table from Phoenix resluts and the function of AUC to get this time, but I am not sure whether this idea is right.
I have search many meterials about glucose-infsion study, this parameter is the secondary end. So it is a common parameter in glucose-infsion study, but I can not find the calculating mathod.:-(

Complete thread:

Activity
 Admin contact
21,749 posts in 4,547 threads, 1,545 registered users;
online 9 (0 registered, 9 guests [including 5 identified bots]).
Forum time: Wednesday 22:20 CEST (Europe/Vienna)

Mediocrity finds safety in standardization.    Frederick E. Crane

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5