AUC-apical? [Software]

posted by Aisha.ma – United Arab Emirates, 2019-10-07 20:43 (1710 d 16:32 ago) – Posting: # 20677
Views: 3,979

Hi Helmut,

❝ BTW, are you referring to this guideline?


Maybe the sponsor had consult this guideline before designing the study . Gir is the glucose-infusion rate.

❝ Just to clarify: Are you interested in the yellow area?

[image]


❝ Doesn’t look like your GIR cause that’s a PK profile but you get the idea. IIRC, this was called AUCapical by the “Two Lászlós” (Endrényi and Tóthfalusi). Have to dig it out.


I need to know time to 50% of GIR-AUC0-8. At the begining, I think that I can use summary table from Phoenix resluts and the function of AUC to get this time, but I am not sure whether this idea is right.
I have search many meterials about glucose-infsion study, this parameter is the secondary end. So it is a common parameter in glucose-infsion study, but I can not find the calculating mathod.:-(

Complete thread:

UA Flag
Activity
 Admin contact
23,056 posts in 4,840 threads, 1,641 registered users;
87 visitors (1 registered, 86 guests [including 10 identified bots]).
Forum time: 13:16 CEST (Europe/Vienna)

Everything is trivial, if you know the answer.    Thomas Jaki

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5