Ahem – number of units? [Dissolution / BCS / IVIVC]

posted by Helmut Homepage – Vienna, Austria, 2019-10-06 18:14  – Posting: # 20670
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Hi ElMaestro,

» » […] Bootstrapping is preferred over ƒ2 even if the validity criteria are met?
»
» I think yours is the right interpretation.

Was also the opinion of some experts at BioBridges. Left the audience speechless.

» And it is free of cost, right? [etc. etc.]

Sure. The problem is the ‘regulatory crep’ I suspected in my post. Jiři showed nice simulations about the false positive rate. To squeeze the lower CL ≥50 is not another league but another sport. How many units will we have to test in the future? 24, 48, 96?

Cheers,
Helmut Schütz
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