Is ƒ2 dead as well – always bootstrapping? [Dissolution / BCS / IVIVC]

posted by ElMaestro  – Belgium?, 2019-10-06 17:54 (416 d 06:16 ago) – Posting: # 20668
Views: 2,161

Hi Hötzi,

» Do I get this right? Bootstrapping is preferred over ƒ2 even if the validity criteria* are met?

I think yours is the right interpretation.
And it is free of cost, right? You have free software to do the calculation albeit the validation steps may be a bit cumbersome if you decide to go for that. It is quite uncomplicated: once you have your dissolution datasets you do the f2 and you do some bootstapping with one extra click, wait a few minutes or hours (or just split seconds if you are using my software, made in C of course) and Bob's your uncle.

I could be wrong, but...

Best regards,
ElMaestro

No, of course you do not need to audit your CRO if it was inspected in 1968 by the agency of Crabongostan.

Complete thread:

Activity
 Admin contact
21,210 posts in 4,426 threads, 1,481 registered users;
online 10 (0 registered, 10 guests [including 7 identified bots]).
Forum time: Wednesday 23:10 CET (Europe/Vienna)

You can’t fix by analysis
what you bungled by design.    Richard J. Light, Judith D. Singer, John B. Willett

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5