Is ƒ2 dead as well – always bootstrapping? [Dissolution / BCS / IVIVC]

posted by ElMaestro  – Denmark, 2019-10-06 15:54 (471 d 17:28 ago) – Posting: # 20668
Views: 2,310

Hi Hötzi,

» Do I get this right? Bootstrapping is preferred over ƒ2 even if the validity criteria* are met?

I think yours is the right interpretation.
And it is free of cost, right? You have free software to do the calculation albeit the validation steps may be a bit cumbersome if you decide to go for that. It is quite uncomplicated: once you have your dissolution datasets you do the f2 and you do some bootstapping with one extra click, wait a few minutes or hours (or just split seconds if you are using my software, made in C of course) and Bob's your uncle.

Pass or fail!
ElMaestro

Complete thread:

Activity
 Admin contact
21,306 posts in 4,443 threads, 1,489 registered users;
online 7 (1 registered, 6 guests [including 5 identified bots]).
Forum time: Wednesday 09:22 UTC (Europe/Vienna)

Power: That which is wielded by the priesthood of
clinical trials, the statisticians, and a stick which they use
to beta their colleagues.    Stephen Senn

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5