Two 2x2 and one 6x3 crossover design [Design Issues]

posted by qzhou – China, 2019-09-24 06:20 (1648 d 07:22 ago) – Posting: # 20643
Views: 2,919

Dear Helmut,

Regarding 6x3 crossover design (with one treatment T and two references R1 and R2), I learned that “Two‐at‐a‐Time Principle” is superior most of time than Pooled ANOVA. Would you evaluate the advantages of two independent 2x2 trials (T vs. R1 and T vs. R2) over the 6x3 crossover design? Actually I have completed the two 2x2 trials. However, someone has challenged me for not conducting it as in 6x3 crossover. Could you please help?

Many thanks,

Bing

Complete thread:

UA Flag
Activity
 Admin contact
22,957 posts in 4,819 threads, 1,636 registered users;
104 visitors (0 registered, 104 guests [including 8 identified bots]).
Forum time: 12:43 CET (Europe/Vienna)

With four parameters I can fit an elephant,
and with five I can make him wiggle his trunk.    John von Neumann

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5