steady state for modified release [Regulatives / Guidelines]

posted by Kelen – Brazil, 2019-09-20 22:04 (2037 d 15:12 ago) – Posting: # 20636
Views: 6,579

I would like to ask help for understand the objetive of the steady state study when you are comparing a MR formulation with a IR formulation. The objective would be compare the effect of the accumulation? Is there any reason to conduct the study only with de highest dose?


Edit: Please follow the Forum’s Policy[Helmut]

Complete thread:

UA Flag
Activity
 Admin contact
23,424 posts in 4,927 threads, 1,701 registered users;
29 visitors (0 registered, 29 guests [including 9 identified bots]).
Forum time: 13:16 CEST (Europe/Vienna)

Do not put your faith in what statistics say until you have carefully
considered what they do not say.    William W. Watt

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5