steady state for modified release [Regulatives / Guidelines]

posted by Kelen – Brazil, 2019-09-20 22:04 (1277 d 05:07 ago) – Posting: # 20636
Views: 4,750

I would like to ask help for understand the objetive of the steady state study when you are comparing a MR formulation with a IR formulation. The objective would be compare the effect of the accumulation? Is there any reason to conduct the study only with de highest dose?

Edit: Please follow the Forum’s Policy. [Helmut]

Complete thread:

UA Flag
Activity
 Admin contact
22,546 posts in 4,721 threads, 1,608 registered users;
18 visitors (0 registered, 18 guests [including 10 identified bots]).
Forum time: 02:12 CET (Europe/Vienna)

Science is the great antidote to the poison
of enthusiasm and superstition.    Adam Smith

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5