steady state for modified release [Regulatives / Guidelines]

posted by Kelen – Brazil, 2019-09-20 20:04  – Posting: # 20636
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I would like to ask help for understand the objetive of the steady state study when you are comparing a MR formulation with a IR formulation. The objective would be compare the effect of the accumulation? Is there any reason to conduct the study only with de highest dose?


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