Evaluation of Heparin as a potentially interfering substance [Bioanalytics]

posted by nobody – 2019-09-11 19:32 (378 d 23:32 ago) – Posting: # 20586
Views: 1,485

Heparin is a polyanion, so: Calculate the amount instilled, the volume of fresh blood used to "flush" this amount to the blood collecting device, the resulting concentration in the blood/plasma sample. Use common sense to asses these numbers.

If in doubt (due to physico-chemical properties of analyte), do some in vitro studies with fresh blood/heparin.

Kindest regards, nobody

Complete thread:

Activity
 Admin contact
21,074 posts in 4,394 threads, 1,468 registered users;
online 5 (0 registered, 5 guests [including 1 identified bots]).
Forum time: Thursday 19:04 CEST (Europe/Vienna)

Enlightenment is man’s emergence from his self-imposed nonage
for which he himself was responsible.
Nonage is the inability to use one’s own intellect
without the direction of another.    Immanuel Kant

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5