R scripts/codes for in-vivo conc. [Dissolution / BCS / IVIVC]

posted by amer – Australia, 2019-09-11 07:35 (2126 d 12:38 ago) – Posting: # 20580
Views: 10,156

Hi Lee,

❝ I don't know if this is what you want. Let me know you still have question about running the codes. I have tested the codes and it works well.


Thanks very much. Yes, it is;however, i don't see the oral bioavailability term in the [PCp] equation in the R-code provided. Shouldn't that include bioavailability when doing convolution? Does it assume, in its current for, that the bioavailability is 100%?

❝ ❝ on the side, just wondering if the ivivc package been validated against standard ivivc software (say WinNonlin?)


❝ Not validated with WLN. Should I? :confused: I do not have WLN. If you have WNL, can you help to validate?


Unfortunately, i dont have access to WLN.

Cheers,

Complete thread:

UA Flag
Activity
 Admin contact
23,428 posts in 4,929 threads, 1,684 registered users;
84 visitors (0 registered, 84 guests [including 12 identified bots]).
Forum time: 20:14 CEST (Europe/Vienna)

No matter what side of the argument you are on,
you always find people on your side
that you wish were on the other.    Thomas Berger

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5