R scripts/codes for in-vivo conc. [Dissolution / BCS / IVIVC]

posted by amer – Australia, 2019-09-11 07:35 (1716 d 22:19 ago) – Posting: # 20580
Views: 6,473

Hi Lee,

❝ I don't know if this is what you want. Let me know you still have question about running the codes. I have tested the codes and it works well.


Thanks very much. Yes, it is;however, i don't see the oral bioavailability term in the [PCp] equation in the R-code provided. Shouldn't that include bioavailability when doing convolution? Does it assume, in its current for, that the bioavailability is 100%?

❝ ❝ on the side, just wondering if the ivivc package been validated against standard ivivc software (say WinNonlin?)


❝ Not validated with WLN. Should I? :confused: I do not have WLN. If you have WNL, can you help to validate?


Unfortunately, i dont have access to WLN.

Cheers,

Complete thread:

UA Flag
Activity
 Admin contact
23,035 posts in 4,835 threads, 1,645 registered users;
43 visitors (0 registered, 43 guests [including 7 identified bots]).
Forum time: 05:55 CEST (Europe/Vienna)

The mediocre teacher tells.
The good teacher explains.
The superior teacher demonstrates.
The great teacher inspires.    William Arthur Ward

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5