R scripts/codes for in-vivo conc. [Dissolution / BCS / IVIVC]

posted by amer – Australia, 2019-09-11 03:35  – Posting: # 20580
Views: 1,826

Hi Lee,

» I don't know if this is what you want. Let me know you still have question about running the codes. I have tested the codes and it works well.

Thanks very much. Yes, it is;however, i don't see the oral bioavailability term in the [PCp] equation in the R-code provided. Shouldn't that include bioavailability when doing convolution? Does it assume, in its current for, that the bioavailability is 100%?

» » on the side, just wondering if the ivivc package been validated against standard ivivc software (say WinNonlin?)
»
» Not validated with WLN. Should I? :confused: I do not have WLN. If you have WNL, can you help to validate?

Unfortunately, i dont have access to WLN.

Cheers,

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