Intrasubject CV for fed studies [PK / PD]

posted by zaibo liu – China, 2019-08-23 00:54  – Posting: # 20508
Views: 677

» Does anyone know if it is possible to estimate the intrasubject CV of a drug for a fed study if only the food effect data is available (and fasting BE study data)?

It is not possible, but intrasubject CV is always small than fasting for BCS II or first pass drug.

Complete thread:

Activity
 Admin contact
20,138 posts in 4,246 threads, 1,388 registered users;
online 6 (0 registered, 6 guests [including 5 identified bots]).
Forum time (Europe/Vienna): 06:37 UTC

It is better to debate a question without settling it
than to settle a question without debating it.    Joseph Joubert

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5