Intrasubject CV for fed studies [PK / PD]

posted by zaibo liu – China, 2019-08-23 02:54 (627 d 06:26 ago) – Posting: # 20508
Views: 1,993

» Does anyone know if it is possible to estimate the intrasubject CV of a drug for a fed study if only the food effect data is available (and fasting BE study data)?

It is not possible, but intrasubject CV is always small than fasting for BCS II or first pass drug.

Complete thread:

 Admin contact
21,446 posts in 4,483 threads, 1,511 registered users;
online 31 (0 registered, 31 guests [including 13 identified bots]).
Forum time: Tuesday 09:21 CEST (Europe/Vienna)

The fact that some geniuses were laughed at
does not imply that all who are laughed at are geniuses.    Carl Sagan

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz