Intrasubject CV for fed studies [PK / PD]

posted by ElMaestro  – Belgium?, 2019-08-22 19:56 (424 d 03:32 ago) – Posting: # 20507
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Hi jag,

» Does anyone know if it is possible to estimate the intrasubject CV of a drug for a fed study if only the food effect data is available (and fasting BE study data)?

It is not readily possible. Both a negative and a positive food effect can be accompanied by a decreased or increased CV. You'll need to work hard for this one :crying:

I could be wrong, but...

Best regards,
ElMaestro

R's base package has 274 reserved words and operators, along with 1761 functions. I can use 18 of them (about 14 of them properly). I believe this makes me the Donald Trump of programming.

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