Bioequivalence and Bioavailability Forum

Intrasubject CV for fed studies [PK / PD]

posted by ElMaestro  – Denmark, 2019-08-22 19:56 (517 d 09:45 ago) – Posting: # 20507
Views: 1,832

Hi jag,

» Does anyone know if it is possible to estimate the intrasubject CV of a drug for a fed study if only the food effect data is available (and fasting BE study data)?

It is not readily possible. Both a negative and a positive food effect can be accompanied by a decreased or increased CV. You'll need to work hard for this one

Complete thread:

• Intrasubject CV for fed studies jag009 2019-08-22 14:53 [PK / PD] 
  • Intrasubject CV for fed studiesElMaestro 2019-08-22 21:56
  • Intrasubject CV for fed studies zaibo liu 2019-08-23 02:54
    • Intrasubject CV for fed studies jag009 2019-09-04 06:32