Not sure whether it makes sense [Design Issues]

posted by abhimanyu – Banglore, 2019-08-03 13:54  – Posting: # 20469
Views: 168

Hi Helmut/SP,

» Maybe it is better to opt for a modified Williams’ design T1T2RR | T2RT1R | RT1RT2 | RRT2T1 which gives
» T1 RR |  RT1R | RT1R  | RR T1 and
»  T2RR | T2R R | R RT2 | RRT2 
» At least balanced for T1 and T2 (once in every period).
» However, we have R twice in periods 1&2 and only once in periods 3&4.


If we consider modified Williams’ design with this sequence T1T2RR | T2RT1R | RT1RT2 | RRT2T1 Then,

What would be change in Proc GlM / Proc Mixed for Calculate Swr, 95% Upper bound (Scaled), and 90% CI (Unscaled):confused::confused:.



Thanking you in advance!!:-)

Abhimanyu

Complete thread:

Activity
 Mix view
Bioequivalence and Bioavailability Forum |  Admin contact
19,687 posts in 4,178 threads, 1,352 registered users;
online 11 (0 registered, 11 guests [including 2 identified bots]).
Forum time (Europe/Vienna): 20:39 CEST

The fundamental cause of trouble in the world today is
that the stupid are cocksure
while the intelligent are full of doubt.    Bertrand Russell

The BIOEQUIVALENCE / BIOAVAILABILITY FORUM is hosted by
BEBAC Ing. Helmut Schütz
HTML5