Tmax and T1/2 [NCA / SHAM]

posted by Ohlbe – France, 2008-07-15 12:33 (6140 d 13:26 ago) – Posting: # 2036
Views: 21,428

Dear Alhas,

The body does not press a button at Tmax to stop absorbing the drug and to start eliminating it. Elimination starts at the second the drug enters the body. Tmax is the time when you reach a balance between absorption and elimination: before Tmax the drug enters the body faster than it is eliminated, and concentrations increase. After Tmax the drug is eliminated faster than it is absorbed, and concentrations decrease.

Regards
Ohlbe

Complete thread:

UA Flag
Activity
 Admin contact
23,424 posts in 4,927 threads, 1,670 registered users;
144 visitors (0 registered, 144 guests [including 14 identified bots]).
Forum time: 02:00 CEST (Europe/Vienna)

Young man, in mathematics you don’t understand things.
You just get used to them.    John von Neumann

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5