## Dose term in the ANOVA Model [Regulatives / Guidelines]

Hello balakotu,

» When i keep totaldose is a factor along with normal fixed effects (seq sub(seq) per trt) the model is not execute, Please let us know what are the fixed effects is required in ANOVA model.
»
» SAS code:
» model Cmax AUCt AUCi= seq sub(seq) per trt totaldose / ss3;» test h= seq e=sub(seq)/htype=3 etype=3;

I am not a SAS user, so I googled this one. It is important to tell the program which ones are fixed factors and which ones are covariates.
Am absolutely not sure, but I believe you might need to use class for seq, sub(seq), per and trt to indicate that those are the fixed effects. For trt and seq this may not be an issue if the stats program does not coerce them to integers or other other numerics. I have no idea if SAS does this in the absence of a class statement.

Otherwise it could have no way to know if you did not mean per and sub(seq) as covariates. Bear in mind the levels of those are typically coded with integers like 1, 2, 3...

Pass or fail!
ElMaestro