Bioequivalence and Bioavailability Forum • Graphing Mean PK profile

Graphing Mean PK profile [🇷 for BE/BA]

posted by nobody – 2019-04-24 16:15 (2246 d 08:11 ago) – Posting: # 20226
Views: 16,682

❝ Some people set all BQLs to zero in order to calculate the arithmetic mean. Others set the first BQL after t_max to LLOQ/2, and, and, and… There will always be a bias.

How would you otherwise calculate the geo. mean profile?

And AUCtlast is a mess with different tlast for T and R and and and. Statistics is always some kind of abstraction. Do a spaghetti plot for T and R and individual T+R for each subject and you might get completely different "ideas" / insights...

—
Kindest regards, nobody

Complete thread:

Graphing Mean PK profile roman_max 2019-04-23 16:01 [🇷 for BE/BA]
- Graphing Mean PK profile Shuanghe 2019-04-23 18:31
  - Graphing Mean PK profile roman_max 2019-04-24 12:29
- Graphing Mean PK profile Helmut 2019-04-23 22:23
  - Graphing Mean PK profile nobody 2019-04-24 11:23
    - Graphing Mean PK profile Helmut 2019-04-24 11:49
      - Graphing Mean PK profile nobody 2019-04-24 11:53
        
        Graphing Mean PK profile Helmut 2019-04-24 12:32
        
        Graphing Mean PK profile nobody 2019-04-24 12:49
  - Graphing Mean PK profile roman_max 2019-04-24 12:36
    - Graphing Mean PK profile Helmut 2019-04-24 13:50
      - Graphing Mean PK profilenobody 2019-04-24 14:15
        
        Graphing Mean PK profile Helmut 2019-04-24 14:41
        
        Pasta Ohlbe 2019-04-25 12:47
        
        Pasta nobody 2019-04-25 14:36
        Spaghetti Viennese Helmut 2019-04-25 14:39
        
        Spaghetti Viennese nobody 2019-04-25 15:08
        
        OT: Blume/Mutschler Helmut 2019-04-25 15:32
        
        OT: Blume/Mutschler nobody 2019-04-25 15:43
  - A lie is a lie is a lie ... d_labes 2019-04-25 19:59