Bioequivalence and Bioavailability Forum • Metrics for absorption

Metrics for absorption [NCA / SHAM]

posted by nobody – 2019-04-16 09:34 – Posting: # 20172
Views: 337
(edited by nobody on 2019-04-16 10:39)

...maybe I got you completely wrong, but for me ka ratio varies 48-fold, while cmax ratio only 2.50-fold, pAUC 4.47-fold and cmax/AUC 2.34-fold over the range tested.

So pAUC is indeed the best of all-not-so-wonderful parameters?

—
Kindest regards, nobody

Complete thread:

Metrics for absorption Helmut 2019-04-15 12:08 [NCA / SHAM]
- Metrics for absorption nobody 2019-04-15 12:15
  - Metrics for absorption ElMaestro 2019-04-15 12:23
    - Metrics for absorption nobody 2019-04-15 12:39
  - Metrics for absorption Helmut 2019-04-15 13:02
    - Metrics for absorption nobody 2019-04-15 13:48
      - Metrics for absorption Helmut 2019-04-15 19:31
        
        Metrics for absorption nobody 2019-04-16 09:34
        
        Metrics for absorption nobody 2019-04-16 15:15
        
        Metrics for absorption Helmut 2019-04-16 17:01
        
        Metrics for absorption nobody 2019-04-17 11:15
        
        Simulation framework mittyri 2019-04-17 01:21
        
        Simulation framework Helmut 2019-04-17 13:31
        
        Conclusion mittyri 2019-04-17 15:42
        
        Conclusion & beyond Helmut 2019-04-17 17:05