Metrics for absorption [NCA / SHAM]

posted by nobody – 2019-04-15 14:15 (2274 d 23:57 ago) – Posting: # 20164
Views: 11,916

Hi

first thought

"Cmax is ...is nonspecific to it (reflects also the extent of absorption as well as the rates of disposition processes),..."

Hmm, how is AUCp not reflecting disposition processes?

"...lacks kinetic sensitivity even following a single administration."

How much sensitivity is needed in the first place? Or are we creating problems by "overly sensitive" methods with no relevance in clinical practice?

Kindest regards, nobody

Complete thread:

UA Flag
Activity
 Admin contact
23,428 posts in 4,929 threads, 1,682 registered users;
48 visitors (0 registered, 48 guests [including 22 identified bots]).
Forum time: 14:12 CEST (Europe/Vienna)

No matter what side of the argument you are on,
you always find people on your side
that you wish were on the other.    Thomas Berger

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5