Bioequivalence and Bioavailability Forum • Don’t weight by 1/s²

Don’t weight by 1/s² [Bioanalytics]

posted by Helmut – Vienna, Austria, 2019-03-18 11:19 (1289 d 20:02 ago) – Posting: # 20046
Views: 4,331

Hi nobody, Ohlbe and everybody,

» » In his response Helmut mentions SD calculated from 2 or 3 replicates. Sorry Helmut, but I would consider any such value as meaningless.
»
» Exactly. Trash in trash out. SD is not erwartungstreu. Start with n=20+...

I stand corrected – you are both right. Is a stupid idea.

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Helmut Schütz

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Complete thread:

Handling BLOQ values (Fisher Info etc.) mittyri 2019-03-16 14:41 [Bioanalytics]
- Handling BLOQ values (Fisher Info etc.) Helmut 2019-03-16 15:39
  - The smartest solution ElMaestro 2019-03-16 22:35
    - An old solution Helmut 2019-03-16 23:05
      - old, obvious? ElMaestro 2019-03-19 08:26
    - Example Helmut 2019-03-17 01:56
  - ADA example mittyri 2019-03-18 22:20
    - My beloved Ada Helmut 2019-03-19 01:34
- Handling BLOQ values (Fisher Info etc.) Ohlbe 2019-03-17 14:32
  - Handling BLOQ values (Fisher Info etc.) nobody 2019-03-18 08:14
    - Don’t weight by 1/s²Helmut 2019-03-18 11:19