Bioequivalence and Bioavailability Forum • Handling BLOQ values (Fisher Info etc.)

Handling BLOQ values (Fisher Info etc.) [Bioanalytics]

posted by nobody – 2019-03-18 09:14 (2258 d 05:24 ago) – Posting: # 20045
Views: 6,922

❝ In his response Helmut mentions SD calculated from 2 or 3 replicates. Sorry Helmut, but I would consider any such value as meaningless.

Exactly. Trash in trash out. SD is not erwartungstreu. Start with n=20+...

—
Kindest regards, nobody

Complete thread:

Handling BLOQ values (Fisher Info etc.) mittyri 2019-03-16 14:41 [Bioanalytics]
- Handling BLOQ values (Fisher Info etc.) Helmut 2019-03-16 15:39
  - The smartest solution ElMaestro 2019-03-16 22:35
    - An old solution Helmut 2019-03-16 23:05
      - old, obvious? ElMaestro 2019-03-19 08:26
    - Example Helmut 2019-03-17 01:56
  - ADA example mittyri 2019-03-18 22:20
    - My beloved Ada Helmut 2019-03-19 01:34
- Handling BLOQ values (Fisher Info etc.) Ohlbe 2019-03-17 14:32
  - Handling BLOQ values (Fisher Info etc.)nobody 2019-03-18 08:14
    - Don’t weight by 1/s² Helmut 2019-03-18 11:19

Admin contact
23,424 posts in 4,927 threads, 1,680 registered users;
37 visitors (0 registered, 37 guests [including 22 identified bots]).
Forum time: 15:38 CEST (Europe/Vienna)

Pharmacokinetics may be simply defined as
what the body does to the drug,
as opposed to pharmacodynamics, which may be defined as
what the drug does to the body. Leslie Z. Benet

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC

Ing. Helmut Schütz