Bioequivalence and Bioavailability Forum • Handling BLOQ values (Fisher Info etc.)

Handling BLOQ values (Fisher Info etc.) [Bioanalytics]

posted by nobody – 2019-03-18 08:14 (1045 d 13:48 ago) – Posting: # 20045
Views: 4,045

» In his response Helmut mentions SD calculated from 2 or 3 replicates. Sorry Helmut, but I would consider any such value as meaningless.

Exactly. Trash in trash out. SD is not erwartungstreu. Start with n=20+...

—
Kindest regards, nobody

Complete thread:

Handling BLOQ values (Fisher Info etc.) mittyri 2019-03-16 14:41 [Bioanalytics]
- Handling BLOQ values (Fisher Info etc.) Helmut 2019-03-16 15:39
  - The smartest solution ElMaestro 2019-03-16 22:35
    - An old solution Helmut 2019-03-16 23:05
      - old, obvious? ElMaestro 2019-03-19 08:26
    - Example Helmut 2019-03-17 01:56
  - ADA example mittyri 2019-03-18 22:20
    - My beloved Ada Helmut 2019-03-19 01:34
- Handling BLOQ values (Fisher Info etc.) Ohlbe 2019-03-17 14:32
  - Handling BLOQ values (Fisher Info etc.)nobody 2019-03-18 08:14
    - Don’t weight by 1/s² Helmut 2019-03-18 11:19